The Ludwig Boltzmann Institute (LBI) for Retinology and biomicroscopic Laser Surgery was established in 1997 at the Department of Ophthalmology, Rudolf Foundation Clinic, Vienna, Austria (Chief: Prof. Dr. Susanne Binder).
Our Institute conducts clinical and experimental research with an exploratory focus on retinal pathologies, especially age related macular degeneration (AMD), optical coherence tomography (OCT) and vitreoretinal diseases.
The main interests in our research on AMD include the evaluation of new treatment modalities and the investigation on the disease’s pathogenesis and its diagnosis. In this context, we also verify our results on intraocular ant- VEGF( vascular endothelial growth factor ) therapies in neovascular AMD and participate in several multi center trials concerning this topic. Autologous transplantation of retinal pigment epithelial cells (RPE), as a possible surgical treatment option for AMD, was started as a research programme in 1998 and is now technically refined and evaluated in prospective clinical trials in the last years. Moreover our Institute conducted cell studies together with the Bascom Palmer Eye Institute and “Tissue Tech” in Miami on amniotic membrane as a basal lamina for RPE transplants, both resulting in several top papers. Other experimental projects with the Stanford University and the University Clinic of Cardiff include the creation of an artificial RPE cell basal layer and the rejuvenation of adult RPE cells. In addition, genetic studies on genes associated with the pathogenesis of AMD have been performed successfully. More recently our institute presented interesting new results on the role of the vitreous interface in AMD pathogenesis that obtained high acceptance in the international scientific community.